Health services are delivered by a range of integrated facilities located across the region. Hospitals at Derby, Broome, Halls Creek, Wyndham, Fitzroy Crossing and Kununurra are complemented by community clinics, which exist in many remote localities. The region has access to a range of specialist services including aged care facilities and rehabilitation services.

The Commonwealth Department of Health and Ageing maintains an office in Broome and the Western Australian Health Department has administrative offices in Derby and Broome.

A significant upgrade to the Broome Hospital has recently been completed and includes the establishment of a new emergency department, doctors' consultancy areas, x-ray and pathology rooms and allied health areas.

A number of independent community health organisations also deliver targeted services into some of the remote communities across the region. 

The Royal Flying Doctor Service Kimberley base at Derby conducts routine clinical and medical consultations in remote communities and pastoral properties. It also provides a 24 hour emergency aero-medical service across the region.